| Full Name | cytohesin 1 |
| Product Description | Rabbit polyclonal antibody to PSCD1 (pleckstrin homology, Sec7 and coiled-coil domains 1) |
| Background | The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2. [provided by RefSeq] |
| Synonyms | B2-1 antibody, CYTOHESIN-1 antibody, D17S811E antibody, FLJ34050 antibody, FLJ41900 antibody, PSCD1 antibody, SEC7 antibody, CYTH1 antibody, homolog of secretory protein SEC7 antibody, "pleckstrin homology, Sec7 and coiled-coil domains 1 antibody", SEC7 homolog B2-1 antibody, cytoadhesin 1 antibody, "PH, SEC7 and coiled-coil domain-containing protein 1 antibody", cytohesin 1 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | PSCD1 |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PSCD1. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Mouse, Rat, Chicken, Rhesus Monkey |
| Predict Reactivity Note | Mouse (97%), Rat (97%), Chicken (97%), Rhesus Monkey (100%) |
| Conjugation | Unconjugated |