|Full Name||cytohesin 4|
|Product Description||Rabbit polyclonal antibody to PSCD4 (pleckstrin homology, Sec7 and coiled-coil domains 4)|
|Background||The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The structures of this gene and CYTH1 are very similar. [provided by RefSeq]|
|Synonyms||CYT4 antibody, DJ63G5.1 antibody, PSCD4 antibody, CYTH4 antibody, "pleckstrin homology, Sec7 and coiled-coil domains 4 antibody", cytohesin-4 antibody, "pleckstrin homology, Sec7 and coiled/coil domains 4 antibody", "PH, SEC7 and coiled-coil domain-containing protein 4 antibody", cytohesin 4 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PSCD4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (100%)|