|Full Name||discs, large homolog 4 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to PSD95 (discs, large homolog 4 (Drosophila))|
|Background||Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.|
|Synonyms||Dlg4 antibody , Dlgh4 antibody , SAP90 antibody , SAP90A antibody , discs, large homolog 4 (Drosophila) antibody|
|Cellular Localization||Membrane , Cell junction , synapse , postsynaptic cell membrane , postsynaptic density , synapse|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human PSD95. The exact sequence is proprietary.|
|Species Reactivity||Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Rhesus Monkey (100%), Bovine (100%)|