PSMD10 antibody [N1C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||24 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||proteasome (prosome, macropain) 26S subunit, non-ATPase, 10|
|Product Description||Rabbit polyclonal antibody to PSMD10 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 10)|
|Background||The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20. [provided by RefSeq]|
|Synonyms||dJ889N15.2 antibody, p28 antibody, p28(GANK) antibody, PSMD10 antibody, hepatocellular carcinoma-associated protein p28-II antibody, 26S proteasome regulatory subunit p28 antibody, ankyrin repeat protein antibody, gankyrin antibody, 26S proteasome non-ATPase regulatory subunit 10 antibody, "proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PSMD10. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Rhesus Monkey|
|Predict Reactivity Note||Mouse (95%), Rat (94%), Chicken (81%), Rhesus Monkey (100%)|