| Full Name | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 |
| Product Description | Rabbit polyclonal to PSMD13 (C-term) |
| Background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 1 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq] |
| Synonyms | 26S proteasome regulatory subunit p40.5, 26S proteasome regulatory subunit S11, 26S proteasome nonATPase regulatory subunit 13, 26S proteasome non-ATPase regulatory subunit 13, 26S proteasome nonATPase regulatory subunit13, PSMD13 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target | PSMD13 |
| Isotype | IgG |
| Immunogen | KLH conjugated synthetic peptide between 266~296 amino acids from the C-terminal region of human PSMD13. |
| Antigen Species | Human |
| Species Reactivity | Human |