|Full Name||proline-serine-threonine phosphatase interacting protein 1|
|Product Description||Rabbit Polyclonal antibody to PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1)|
|Background||The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq]|
|Synonyms||proline-serine-threonine phosphatase interacting protein 1 Antibody , PAPAS Antibody , H-PIP Antibody , CD2BP1S Antibody , CD2BP1 Antibody , PSTPIP Antibody , CD2BP1L Antibody|
|Cellular Localization||Cytoplasm (By similarity) , Cytoplasm , cytoskeleton (By similarity) , Cell projection , lamellipodium (By similarity) , perinuclear region (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human PSTPIP1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (83%), Rat (80%), Pig (85%), Bovine (86%)|