|Full Name||parathyroid hormone-like hormone|
|Product Description||Rabbit Polyclonal antibody to PTHLH (parathyroid hormone-like hormone)|
|Background||The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq]|
|Synonyms||BDE2 antibody, HHM antibody, MGC14611 antibody, PLP antibody, PTHR antibody, PTHRP antibody, PTHLH antibody, osteostatin antibody, parathyroid hormone-related protein antibody, PTH-related protein antibody, parathyroid hormone-like related protein antibody, PTH-rP antibody, parathyroid hormone-like hormone antibody|
|Cellular Localization||Cytoplasm , Nucleus , Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PTHLH. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (85%), Rat (89%), Dog (92%), Pig (91%), Rabbit (88%), Rhesus Monkey (99%), Bovine (91%)|