|Full Name||protein tyrosine phosphatase type IVA, member 3|
|Product Description||Rabbit Polyclonal antibody to PTP4A3 (protein tyrosine phosphatase type IVA, member 3)|
|Background||The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq]|
|Synonyms||PRL-3 antibody, PRL-R antibody, PRL3 antibody, PTP4A3 antibody, protein-tyrosine phosphatase 4a3 antibody, protein tyrosine phosphatase type IVA 3 antibody, protein-tyrosine phosphatase of regenerating liver 3 antibody, potentially prenylated protein tyrosine phosphatase antibody, "protein tyrosine phosphatase type IVA, member 3 antibody"|
|Cellular Localization||Cell membrane , Early endosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human PTP4A3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Zebrafish, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (96%), Rat (96%), Zebrafish (87%), Xenopus laevis (90%), Rhesus Monkey (100%), Bovine (94%)|