| Full Name | parkin RBR E3 ubiquitin protein ligase |
| Background | The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008] |
| Synonyms | parkin RBR E3 ubiquitin protein ligase Antibody , LPRS2 Antibody , PRKN Antibody , PARK2 Antibody , PDJ Antibody , AR-JP Antibody |
| Specificity | PARK2 antibody is human specific. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Parkin antibody was raised against a 17 amino acid peptide near the amino terminus of human Parkin.The immunogen is located within amino acids 110 - 160 of Parkin. |
| Antigen Species | Human |
| Species Reactivity | Human |
| Conjugation | Unconjugated |