|Full Name||plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)|
|Product Description||Rabbit Polyclonal antibody to Plakophilin 1 (plakophilin 1 (ectodermal dysplasia/skin fragility syndrome))|
|Background||This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. [provided by RefSeq]|
|Synonyms||B6P antibody, MGC138829 antibody, PKP1 antibody, plakophilin-1 antibody, band 6 protein antibody, plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) antibody|
|Cellular Localization||Isoform 1: Nucleus , Cell junction , desmosome , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Plakophilin 1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (96%), Dog (95%), Bovine (95%)|