|Full Name||poliovirus receptor|
|Product Description||Rabbit Polyclonal antibody to Poliovirus Receptor (poliovirus receptor)|
|Background||The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||PVR Antibody , PVS Antibody , Necl-5 Antibody , HVED Antibody , NECL5 Antibody , poliovirus receptor Antibody , TAGE4 Antibody , CD155 Antibody|
|Cellular Localization||Isoform Alpha: Cell membrane; Single-pass type I membrane protein , Isoform Delta: Cell membrane; Single-pass type I membrane protein , Isoform Beta: Secreted , Isoform Gamma: Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Poliovirus Receptor. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rhesus Monkey (90%)|