|Full Name||polycystic kidney disease 2 (autosomal dominant)|
|Product Description||Rabbit Polyclonal antibody to Polycystin 2 (polycystin-2)|
|Background||This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease. [provided by RefSeq]|
|Synonyms||APKD2 antibody, MGC138466 antibody, MGC138468 antibody, PC2 antibody, PKD4 antibody, Pc-2 antibody, TRPP2 antibody, PKD2 antibody, autosomal dominant polycystic kidney disease type II protein antibody, polycystwin antibody, polycystin-2 antibody, "transient receptor potential cation channel, subfamily P, member 2 antibody", R48321 antibody, polycystic kidney disease 2 (autosomal dominant) antibody|
|Cellular Localization||Membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Polycystin 2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Chicken, Bovine|
|Predict Reactivity Note||Mouse (92%), Rat (87%), Pig (98%), Chicken (84%), Bovine (97%)|