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1 .GTX78229 PTBP1 antibody [SH54]

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PTBP1 antibody [SH54]

Host / ClonalityMouse Monoclonal
Clone NameSH54
ApplicationsICC/IF, IHC-P, WB
Species reactivityHuman

Cat No:

GTX78229

Package	Price	Qty
100 μg	USD 319.00

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Application Information: PTBP1 antibody [SH54]

Catalog Number	GTX78229 ☆☆☆☆☆ ( 0 ) ( 0 )
Product Name	PTBP1 antibody [SH54] See all PTBP1 products
Applications	ICC/IF, IHC-P, WB
Application Note	IHC-FFPE (2.5 ug/ml), IF (1-3 ug/ml), Western blot (1.0 ug/ml)
Form Supplied	Liquid

Specifications: PTBP1 antibody [SH54]

Full Name	polypyrimidine tract binding protein 1
Product Description	Mouse monoclonal antibody [5H54] to PTBP1
Background	Polypyrimidine tract binding protein (PTB) is an abundant vertebrate hnRNP protein that functions as a splicing regulator with multiple targets. PTB exists as a 57 kDa protein that is found exclusively in the perinucleolar compartment (PNC) and regulates alternative splicing by binding to a specific pyrimidine tract sequence that is typically found near the 3' end of introns. The PNC in turn is a structure that is more prevalent in cancer cells than in normal cells. This latter observation suggests the possibility of using expression of PTB as a marker for tumor cells. In solution phase, PTB exists as a homodimer and in some cancer cells exists as two isoforms, the ratio of which appears to correlate with metastatic potential particularly in prostatic carcinoma. PTB is involved in the regulation of many different viral genomes such as that of hepatitis C virus.
Synonyms	HNRNP-I, HNRNPI, HNRPI, MGC10830, MGC8461, PTB, PTB-1, PTB-T, PTB2, PTB3, PTB4, pPTB, PTB 1, PTB T, HNRNP I, PTB1, PTBT
Host	Mouse
Clonality	Monoclonal
Clone Name	SH54
Isotype	IgG1
Immunogen	Mice were immunized with human HeLa nuclear extract and fusing the splenocytes with Sp2/0 mouse myeloma cells.
Antigen Species	Human
Species Reactivity	Human

Storage Conditions: PTBP1 antibody [SH54]

Storage Buffer	100 ug purified IgG1 with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA.
Storage Instruction	Store at -20º C. Avoid multiple freeze/thaw cycles.
Notes	For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
Disease Related > Alzheimer's disease Disease Related > Cardiovascular > Heart > Heart disease Neuroscience > Disorder > Alzheimer's disease More Hide

PTBP1 antibody [SH54] validated data

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