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CCR8 antibody [4G19]

Anti-CCR8 antibody [4G19] used in Flow cytometry (FACS). GTX52519

Cat. No. GTX52519

Host

 Rat

Clonality

 Monoclonal

Clone Name

 4G19

Isotype

 IgG2

Application

 FACS

Reactivity

 Human
Package
50 μg ($399)
See all CCR8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 1:100 - 1:800
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human CCR8 transfected 293 cells

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CC motif chemokine receptor 8 , CCCKR8 , CCR8 , CDw198 , CKRL1 , CMKBR8 , CMKBRL2 , CY6 , GPRCY6 , TER1 , CD198 , C-C motif chemokine receptor 8

Cellular Localization

Cell membrane

Background

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CCR8 antibody [4G19] used in Flow cytometry (FACS). GTX52519

GTX52519 FACS Image

FACS analysis of human PBMCs using GTX52519 CCR8 antibody [4G19].
Antibody amount : 1x10⁶/3μg

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399