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CD105 antibody [MEM-229]

Anti-CD105 antibody [MEM-229] used in IHC (Frozen sections) (IHC-Fr). GTX78404

Cat. No. GTX78404

Reference 6

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MEM-229

Isotype

 IgG2a

Application

 WB, ICC/IF, IHC-Fr, FACS

Reactivity

 Human, Pig
Package
100 μg ($399)
See all CD105 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Product Note

We do not recommend use of this product for Dog,Horse samples.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_625626

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

END , ENG , HHT1 , ORW1 , endoglin , CD105

Cellular Localization

Cell membrane

Background

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Anti-CD105 antibody [MEM-229] used in IHC (Frozen sections) (IHC-Fr). GTX78404

GTX78404 IHC-Fr Image

IHC-Fr analysis of infarcted pig heart tissue using GTX78404 CD105 antibody [MEM-229].
Green : Primary antibody
Blue : DAPI
Diultion : 5μg/ml

REFERENCE

Application Reference

Khatri M et al. J Cell Physiol 2017; (Epub) Therapeutic potential of porcine bronchoalveolar fluid-derived mesenchymal stromal cells in a pig model of LPS-induced ALI.
Application : FACS
Reactivity : Pig
Khatri M et al. Stem Cell Res Ther 2015; 6 : 222 Porcine lung mesenchymal stromal cells possess differentiation and immunoregulatory properties.
Application : FACS
Reactivity : Pig
Yang J et al. J Res Med Sci 2014; 19 (2) : 112-6 Adipose-derived stem cells from the breast.
Application : ICC/IF
Reactivity : Human
Tan Y et al. Tissue Eng Part A 2010; 16 (1) : 67-79 Meniscus reconstruction through coculturing meniscus cells with synovium-derived stem cells on small intestine submucosa--a pilot study to engineer meniscus tissue constructs.
Application : FACS
Reactivity : Pig

Clone Reference

Pei M et al. J Cell Physiol 2012; 227 (5):2163-74 Extracellular matrix deposited by synovium-derived stem cells delays replicative senescent chondrocyte dedifferentiation and enhances redifferentiation.
Application : FACS
Reactivity : Pig
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399