APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 9 - 14 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Baboon, Chimpanzee, Elephant, Gibbon, Gorilla, Lizard, Marmoset, Opossum, Orangutan, Turkey, Platypus(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human CXCR4.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375166
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-X-C motif chemokine receptor 4 , CD184 , CXC motif chemokine receptor 4 , CXCR4 , D2S201E , FB22 , HM89 , HSY3RR , LAP3 , LCR1 , LESTR , NPY3R , NPYR , NPYRL , NPYY3R , WHIM , WHIMS
Cellular Localization
Cell membrane,Cell junction,Early endosome,Late endosome,Lysosome
Background
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX70531 IHC-P Image
IHC-P analysis of human tonsil tissue using GTX70531 CXCR4 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX70531 IHC-P Image
IHC-P analysis of human colon, carcinoma tissue using GTX70531 CXCR4 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX70531 IHC-P Image
IHC-P analysis of lung, small cell carcinoma tissue using GTX70531 CXCR4 antibody.
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GTX70531 IHC-P Image
IHC-P analysis of brain cerebellum purkinje neuron tissue using GTX70531 CXCR4 antibody.
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GTX70531 IHC-P Image
IHC-P analysis of human lymph node, non-hodgkins lymphoma tissue using GTX70531 CXCR4 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
There are currently no references for CXCR4 antibody (GTX70531). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for CXCR4 antibody (GTX70531). Be the first to share your experience with this product.
