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FABP3 antibody [66E2]

Cat. No. GTX54423

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 66E2

Isotype

 IgG1

Application

 WB, IHC-Fr, IP, ELISA

Reactivity

 Human, Mouse, Rat, Pig
Package
50 μg ($399)
See all FABP3 products
PRODUCT

Summary

The monoclonal antibody 66E2 can be used to detect ischemia areas of human heart. It is also useful as marker for brain damage.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1μg/ml
IHC-Fr Assay dependent
IP Assay dependent
ELISA Assay dependent

Note :

WB
Reduced sample treatment.

IHC-Fr
Permeabilization was done in cold acetone with 0.5% hydrogen peroxidase for 10 min, after drying and washing, antibodies were incubated for 30 minutes.

IP
Biotinylated 66E2 was immobilized on streptavidin beads and added to serum to immunoprecipitate H-FABP.
Not tested in other applications.

Calculated MW

15 kDa. ( Note )

Product Note

This antibody is useful for the purification of H-FABP.

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

100 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human H-FABP

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

FABP11,FABP3,HFABP,MDGI,MFABP,OFABP,fatty acid binding protein 3,H-FABP,Cardiac FABP

Cellular Localization

Cytoplasm

Background

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399