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PAR4 antibody, Internal

Anti-PAR4 antibody, Internal used in Western Blot (WB). GTX77887
Anti-PAR4 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX77887
Anti-PAR4 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX77887

Cat. No. GTX77887

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all PAR4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

Positive Control

Jurkat

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to an Internal region of Human PAR4.

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_424835

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

pro-apoptotic WT1 regulator , PAR4 , Par-4

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-PAR4 antibody, Internal used in Western Blot (WB). GTX77887

GTX77887 WB Image

WB analysis of Jurkat cells using GTX77887 PAWR antibody at 0.5-1.0μg/ml.

Anti-PAR4 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX77887

GTX77887 IHC-P Image

IHC-P analysis of human liver tissue using GTX77887 PAWR antibody at 4.0-8.0μg/ml.

Anti-PAR4 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX77887

GTX77887 IHC-P Image

IHC-P analysis of human kidney tissue using GTX77887 PAWR antibody at 4.0-8.0μg/ml.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399