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United States (US)

PPAR gamma antibody

Cat. No. GTX19481

Reference 7

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat, Bovine, Dog, Hamster, Chicken, Pig
Package
200 μg ($399)
See all PPAR gamma products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:400
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Product Note

React with PPARgamma1 and PPARgamma2.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.2% Gelatin

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide mapping near the carboxy terminus of human PPARgamma.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_425200

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

peroxisome proliferator activated receptor gamma , CIMT1 , GLM1 , NR1C3 , PPARG1 , PPARG2 , PPARgamma

Cellular Localization

Nucleus , Cytoplasm

Background

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Guo JW et al. Exp Ther Med 2021; 21 (5) : 448 Magnolol may contribute to barrier function improvement on imiquimod-induced psoriasis-like dermatitis animal model via the downregulation of interleukin-23.
Application : IHC-P
Reactivity : Mouse
Liu H et al. Diabetes Metab Syndr Obes 2020; 13 : 3075-3087 Liraglutide and Insulin Have Contrary Effects on Adipogenesis of Human Adipose-Derived Stem Cells via Wnt Pathway.
Application : WB
Reactivity : Human
Hwang HJ et al. J Cell Physiol 2018; (Epub) zafirlukast promotes * secretion by increasing calcium influx through l-type calcium channels.
Application : IHC-P
Reactivity : Rat
Jhuang HJ et al. Oncotarget 2015; 6 (10) : 7788-803 Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1α-dependent pathway.
Application : WB
Reactivity : Human
Davide P et al. Cell Mol Gastroenterol Hepatol 2015; 1 (6) : 646-663 Lipid-Induced Hepatocyte-Derived Extracellular Vesicles Regulate Hepatic Stellate Cells via MicroRNA Targeting Peroxisome Proliferator-Activated Receptor γ.
Application : WB
Reactivity : Human
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Package List Price ($)
$ 399