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p63 antibody [4E5]

Anti-p63 antibody [4E5] used in Western Blot (WB). GTX60407
Anti-p63 antibody [4E5] used in ELISA (ELISA). GTX60407
Anti-p63 antibody [4E5] used in IHC (Paraffin sections) (IHC-P). GTX60407

Cat. No. GTX60407

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4E5

Isotype

 IgG1

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat, Monkey
Package
100 μl ($409)
See all p63 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

77 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthesized peptide of human p63α.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tumor protein p63 , AIS , B(p51A) , B(p51B) , EEC3 , KET , LMS , NBP , OFC8 , RHS , SHFM4 , TP53CP , TP53L , TP73L , p40 , p51 , p53CP , p63 , p73H , p73L

Cellular Localization

Nucleus

Background

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-l

Database

Research Area

DATA IMAGES

Anti-p63 antibody [4E5] used in Western Blot (WB). GTX60407

GTX60407 WB Image

WB analysis of A431 (1), HeLa (2), Jurkat (3), THP-1 (4), NIH3T3 (5), Cos7 (6) and PC-12 (7) cell lysate using GTX60407 p63 antibody [4E5].

Anti-p63 antibody [4E5] used in ELISA (ELISA). GTX60407

GTX60407 ELISA Image

ELISA analysis of antigen using GTX60407 p63 antibody [4E5].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng

Anti-p63 antibody [4E5] used in IHC (Paraffin sections) (IHC-P). GTX60407

GTX60407 IHC-P Image

IHC-P analysis of ovarian cancer (left) and lung cancer (right) using GTX60407 p63 antibody [4E5].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 409