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p63 antibody [TP63/1786]

Anti-p63 antibody [TP63/1786] used in Protein Array (Protein Array). GTX34944
Anti-p63 antibody [TP63/1786] used in Western Blot (WB). GTX34944
Anti-p63 antibody [TP63/1786] used in Western Blot (WB). GTX34944

Cat. No. GTX34944

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 TP63/1786

Isotype

 IgG2b

Application

 WB, ELISA, Protein Array

Reactivity

 Human
Package
100 μg ($529)
See all p63 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
ELISA Assay dependent
Protein Array Assay dependent

Note :

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
Not tested in other applications.

Calculated MW

77 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (around aa 3-106) of human p63 protein (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

AIS , B(p51A) , B(p51B) , EEC3 , KET , LMS , NBP , OFC8 , RHS , SHFM4 , TP53CP , TP53L , TP63 , TP73L , p40 , p51 , p53CP , p63 , p73H , p73L , tumor protein p63

Cellular Localization

Nucleus

Background

This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016]

Database

Research Area

DATA IMAGES

Anti-p63 antibody [TP63/1786] used in Protein Array (Protein Array). GTX34944

GTX34944 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using p63 Mouse Monoclonal Antibody (TP63/1786). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Anti-p63 antibody [TP63/1786] used in Western Blot (WB). GTX34944

GTX34944 WB Image

WB analysis of recombinant p63 protein, PC3, and HeLa cell lysates using GTX34944 p63 antibody [TP63/1786].

Anti-p63 antibody [TP63/1786] used in Western Blot (WB). GTX34944

GTX34944 WB Image

WB analysis of MCF-7, T47D, and MDA-MB453 cell lysates using GTX34944 p63 antibody [TP63/1786].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529