|Full Name||prohibitin 2|
|Product Description||Rabbit Polyclonal antibody to Prohibitin 2 (prohibitin 2)|
|Background||Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging. |
|Synonyms||BAP antibody, BCAP37 antibody, Bap37 antibody, MGC117268 antibody, PNAS-141 antibody, REA antibody, p22 antibody, PHB2 antibody, B-cell receptor-associated protein BAP37 antibody, prohibitin-2 antibody, B-cell associated protein antibody, D-prohibitin antibody, repressor of estrogen receptor activity antibody, prohibitin 2 antibody|
|Cellular Localization||Mitochondrion inner membrane (By similarity) , Cytoplasm (By similarity) , Nucleus (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Prohibitin 2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Xenopus laevis (86%), Pig (98%), Chicken (94%), Rhesus Monkey (100%), Bovine (99%)|