|Full Name||proteasome (prosome, macropain) subunit, alpha type, 3|
|Product Description||Rabbit Polyclonal antibody to Proteasome 20S alpha 3 (proteasome (prosome, macropain) subunit, alpha type, 3)|
|Background||The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||HC8 antibody, MGC12306 antibody, MGC32631 antibody, PSC3 antibody, PSMA3 antibody, proteasome subunit alpha type-3 antibody, proteasome subunit C8 antibody, multicatalytic endopeptidase complex subunit C8 antibody, proteasome component C8 antibody, macropain subunit C8 antibody, proteasome (prosome, macropain) subunit, alpha type, 3 antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Proteasome 20S alpha 3. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (90%), Chicken (96%), Rhesus Monkey (100%), Bovine (100%)|