|Full Name||proteasome (prosome, macropain) subunit, beta type, 3|
|Product Description||Rabbit Polyclonal antibody to Proteasome 20S beta 3 (proteasome (prosome, macropain) subunit, beta type, 3)|
|Background||The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12. [provided by RefSeq]|
|Synonyms||HC10-II antibody, MGC4147 antibody, PSMB3 antibody, proteasome chain 13 antibody, proteasome component C10-II antibody, proteasome subunit beta type-3 antibody, proteasome theta chain antibody, "proteasome (prosome, macropain) subunit, beta type, 3 antibody"|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Full length human Proteasome 20S beta 3 Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Dog, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (91%), Dog (99%), Pig (97%), Rhesus Monkey (99%), Bovine (99%)|