|Full Name||proteasome (prosome, macropain) subunit, beta type, 4|
|Product Description||Rabbit polyclonal antibody to Proteasome beta 4 (proteasome (prosome, macropain) subunit, beta type, 4)|
|Background||The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. [provided by RefSeq]|
|Synonyms||HN3 antibody, HsN3 antibody, PROS-26 antibody, PROS26 antibody, PSMB4 antibody, macropain beta chain antibody, "proteasome subunit, beta type, 4 antibody", multicatalytic endopeptidase complex beta chain antibody, proteasome beta chain antibody, 26 kDa prosomal protein antibody, proteasome chain 3 antibody, proteasome subunit beta type-4 antibody, hsBPROS26 antibody, proteasome subunit HsN3 antibody, "proteasome (prosome, macropain) subunit, beta type, 4 antibody"|
|Cellular Localization||Cytoplasm (By similarity) , Nucleus |
|Target||Proteasome beta 4|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Proteasome beta 4. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus Tropicalis, Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (96%), Rat (94%), Xenopus Tropicalis (80%), Pig (96%), Rabbit (96%), Rhesus Monkey (99%), Bovine (96%)|