|Full Name||protein C (inactivator of coagulation factors Va and VIIIa)|
|Product Description||Rabbit Polyclonal antibody to Protein C (vitamin K-dependent protein C)|
|Background||The PROC gene encodes protein C (EC 188.8.131.52), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930; MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5; MIM 612309) and VIII (F8; see MIM 306700). Protein S (PROS1; MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM]|
|Synonyms||APC antibody, PC antibody, PROC1 antibody, PROC antibody, vitamin K-dependent protein C antibody, anticoagulant protein C antibody, blood coagulation factor XIV antibody, autoprothrombin IIA antibody, protein C (inactivator of coagulation factors Va and VIIIa) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Protein C. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Dog (81%)|