|Full Name||coagulation factor II (thrombin)|
|Product Description||Rabbit Polyclonal antibody to Prothrombin (coagulation factor II (thrombin))|
|Background||Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq]|
|Synonyms||PT antibody, F2 antibody, prothrombin antibody, serine protease antibody, prothrombin B-chain antibody, coagulation factor II (thrombin) antibody|
|Cellular Localization||Secreted , extracellular space |
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human Prothrombin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rhesus Monkey (96%), Bovine (80%)|