|Full Name||proline rich 5 (renal)|
|Product Description||Rabbit Polyclonal antibody to Protor 1 (proline-rich protein 5)|
|Background||This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq]|
|Synonyms||FLJ20185 antibody, FLJ20185k antibody, PP610 antibody, PROTOR-1 antibody, PROTOR1 antibody, PRR5 antibody, protein observed with Rictor-1 antibody, proline-rich protein 5 antibody, proline rich 5 (renal) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Protor 1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig|
|Predict Reactivity Note||Mouse (89%), Rat (88%), Dog (86%), Pig (84%)|