Pumilio 1 antibody [C2C3], C-term
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||126 kDa (note)
|Positive Controls||293T , A431 , Jurkat , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||pumilio homolog 1 (Drosophila)|
|Product Description||Rabbit Polyclonal antibody to Pumilio 1 (pumilio homolog 1 (Drosophila))|
|Background||This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]|
|Synonyms||HSPUM antibody, KIAA0099 antibody, PUMH antibody, PUMH1 antibody, PUML1 antibody, PUM1 antibody, pumilio-1 antibody, pumilio homolog 1 antibody, pumilio homolog 1 (Drosophila) antibody|
|Cellular Localization||Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human Pumilio 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Chicken, Bovine|
|Predict Reactivity Note||Rat (100%), Zebrafish (93%), Chicken (98%), Bovine (99%)|