|Full Name||quaking homolog, KH domain RNA binding (mouse)|
|Product Description||Rabbit Polyclonal antibody to QK1 (quaking homolog, KH domain RNA binding (mouse))|
|Background||QKI belongs to a family of RNA-binding proteins that have an HNRNPK (MIM 600712) homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1; MIM 602489) and SF1 (MIM 601516) (Chen and Richard, 1998 [PubMed 9671495]). QKI proteins regulate RNA splicing, export of target RNAs from the nucleus, translation of proteins, and RNA stability (Lauriat et al., 2008 [PubMed 17918747]).[supplied by OMIM]|
|Synonyms||DKFZp586I0923 antibody, Hqk antibody, QK antibody, QK1 antibody, QK3 antibody, QKI antibody, protein quaking antibody, "quaking homolog, KH domain RNA binding antibody", RNA binding protein HQK antibody, homolog of mouse quaking QKI (KH domain RNA binding protein) antibody, "quaking homolog, KH domain RNA binding (mouse) antibody"|
|Cellular Localization||Nucleus (By similarity) , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human QK1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Dog, Cat, Pig, Chicken, Bovine|
|Predict Reactivity Note||Xenopus laevis (93%), Dog (100%), Cat (100%), Pig (100%), Chicken (98%), Bovine (100%)|