|Full Name||cadherin 4, type 1, R-cadherin (retinal)|
|Product Description||Rabbit Polyclonal antibody to R-cadherin (cadherin 4, type 1, R-cadherin (retinal))|
|Background||This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. [provided by RefSeq]|
|Synonyms||CDH4 Antibody, CAD4 Antibody, RCAD Antibody, cadherin 4, type 1, R-cadherin (retinal) Antibody|
|Cellular Localization||Cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human R-cadherin. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%), Chicken (91%)|