|Full Name||RAB7A, member RAS oncogene family|
|Product Description||Rabbit Polyclonal antibody to Rab7 (RAB7A, member RAS oncogene family)|
|Background||RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq]|
|Synonyms||PRO2706 antibody , RAB7A antibody , RAB7A, member RAS oncogene family antibody , Rab7 antibody , Rab7 antibody|
|Cellular Localization||Late endosome , Lysosome , Cytoplasmic vesicle , phagosome , Melanosome|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Rab7. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Xenopus laevis, Dog, Sheep, Bovine|
|Predict Reactivity Note||Xenopus laevis (100%), Dog (100%), Sheep (100%), Bovine (100%)|