Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||21 kDa (note)
|Positive Controls||293T , A431 , HeLa , HepG2 , Molt-4 , Raji , mouse liver|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)|
|Product Description||Rabbit Polyclonal antibody to RAC1 (ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1))|
|Background||The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||MGC111543 antibody, TC-25 antibody, p21-Rac1 antibody, RAC1 antibody, ras-related C3 botulinum toxin substrate 1 antibody, ras-like protein TC25 antibody, cell migration-inducing gene 5 protein antibody, "ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody"|
|Cellular Localization||Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity) , Melanosome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RAC1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Drosophila, Xenopus laevis, Dog, Chicken, Sheep, Chimpanzee, Bovine|
|Predict Reactivity Note||Drosophila (82%), Xenopus laevis (90%), Dog (90%), Chicken (90%), Sheep (90%), Chimpanzee (90%), Bovine (90%)|