|Full Name||Rac GTPase activating protein 1|
|Product Description||Rabbit Polyclonal antibody to RACGAP1 (Rac GTPase activating protein 1)|
|Background||Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM]|
|Synonyms||HsCYK-4 antibody, ID-GAP antibody, MgcRacGAP antibody, RACGAP1 antibody, male germ cell RacGap antibody, rac GTPase-activating protein 1 antibody, protein CYK4 homolg antibody, GTPase activating protein antibody, Rac GTPase activating protein 1 antibody|
|Cellular Localization||Nucleus , Cytoplasm , Spindle , Acrosome |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human RACGAP1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey|
|Predict Reactivity Note||Mouse (81%), Rat (82%), Rhesus Monkey (100%)|