|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||72 kDa (note)
|Positive Controls||K562 , THP-1 , HL-60 , NIH-3T3 , JC , BCL-1|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||RAD21 homolog (S. pombe)|
|Product Description||Rabbit Polyclonal antibody to RAD21 (RAD21 homolog (S. pombe))|
|Background||The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq]|
|Synonyms||FLJ25655 antibody, FLJ40596 antibody, HR21 antibody, HRAD21 antibody, KIAA0078 antibody, MCD1 antibody, NXP1 antibody, SCC1 antibody, hHR21 antibody, RAD21 antibody, double-strand-break repair protein rad21 homolog antibody, protein involved in DNA double-strand break repair antibody, SCC1 homolog antibody, nuclear matrix protein 1 antibody, NXP-1 antibody, RAD21 homolog (S. pombe) antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RAD21. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (98%), Xenopus laevis (90%), Chicken (94%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (98%)|