|Full Name||RAE1 RNA export 1 homolog (S. pombe)|
|Product Description||Rabbit polyclonal antibody to RAE1 (RAE1 RNA export 1 homolog (S. pombe))|
|Background||Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||FLJ30608 antibody, MGC117333 antibody, MGC126076 antibody, MGC126077 antibody, MIG14 antibody, MRNP41 antibody, Mnrp41 antibody, dJ481F12.3 antibody, dJ800J21.1 antibody, RAE1 antibody, rae1 protein homolog antibody, migration-inducing gene 14 antibody, homolog of yeast Rae1 (Bharathi) mRNA-associated protein of 41 kDa (Kraemer) antibody, mRNA export protein antibody, mRNA-associated protein MRNP 41 antibody, mRNA export factor antibody, "mRNA-binding protein, 41-kD antibody", RAE1 RNA export 1 homolog (S. pombe) antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RAE1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Pig, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Chimpanzee (100%), Bovine (100%)|