| Full Name | ralA binding protein 1 |
| Background | Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin. |
| Synonyms | RIP1, RALBP1, RIP, RLIP76 |
| Specificity | GTX83734 is specific for human RALBP1 (NP_006779). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Name | 2A6 |
| Isotype | IgG1 |
| Immunogen | Full length human recombinant protein of human RALBP1 (NP_006779) produced in HEK293T cell. |
| Antigen Species | Human |
| Species Reactivity | Human |
| Conjugation | Unconjugated |