|Full Name||RAP2A, member of RAS oncogene family|
|Product Description||Rabbit Polyclonal antibody to RAP2A (RAP2A, member of RAS oncogene family)|
|Background||Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.|
|Synonyms||K-REV antibody, KREV antibody, RAP2 antibody, RbBP-30 antibody, RAP2A antibody, "RAP2, member of RAS oncogene family (K-rev) antibody", ras-related protein Rap-2a antibody, "RAP2A, member of RAS oncogene family antibody"|
|Cellular Localization||Cell membrane; Lipid-anchor; Cytoplasmic side |
|Immunogen||Full length human RAP2A Recombinant protein.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Xenopus laevis, Sheep, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (99%), Xenopus laevis (98%), Sheep (98%), Rhesus Monkey (99%), Bovine (99%)|