|Full Name||RAS p21 protein activator 3|
|Product Description||Rabbit Polyclonal antibody to RASA3 (RAS p21 protein activator 3)|
|Background||The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq]|
|Synonyms||GAP1IP4BP antibody, GAPIII antibody, MGC46517 antibody, MGC47588 antibody, RASA3 antibody, "Ins(1,3,4,5)P4-binding protein antibody", GAP1(IP4BP) antibody, ras GTPase-activating protein 3 antibody, GTPase activating protein III antibody, ins P4-binding protein antibody, "inositol 1,3,4,5-tetrakisphosphate-binding protein antibody", RAS p21 protein activator 3 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human RASA3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (92%), Xenopus laevis (86%), Chicken (90%), Bovine (92%)|