|Full Name||RAS guanyl releasing protein 2 (calcium and DAG-regulated)|
|Product Description||Rabbit Polyclonal antibody to RASGRP2 (RAS guanyl releasing protein 2 (calcium and DAG-regulated))|
|Background||The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||CALDAG-GEFI antibody, CDC25L antibody, RASGRP2 antibody, RAS guanyl nucleotide-releasing protein 2 antibody, calcium and DAG-regulated guanine nucleotide exchange factor I antibody, F25B3.3 kinase-like protein antibody, RAS guanyl-releasing protein 2 antibody, cdc25-like protein antibody, guanine exchange factor MCG7 antibody, calcium and diacylglycerol-regulated guanine nucleotide exchange factor I antibody, hCDC25L antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) antibody|
|Cellular Localization||Cytoplasm , cytosol , Cell membrane; Peripheral membrane protein , Cell junction , synapse , synaptosome (Potential) , Cell projection , ruffle membrane; Peripheral membrane protein (Potential) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RASGRP2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Rabbit, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (96%), Pig (97%), Rabbit (96%), Rhesus Monkey (99%), Bovine (95%)|