|Full Name||recombination signal binding protein for immunoglobulin kappa J region|
|Product Description||Rabbit polyclonal antibody to RBP-Jkappa (recombination signal binding protein for immunoglobulin kappa J region)|
|Background||Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.|
|Synonyms||CBF1 antibody, IGKJRB antibody, IGKJRB1 antibody, KBF2 antibody, MGC61669 antibody, RBP-J antibody, RBPJK antibody, RBPSUH antibody, SUH antibody, csl antibody, RBPJ antibody, suppressor of hairless homolog antibody, RBP-JK antibody, CBF-1 antibody, renal carcinoma antigen NY-REN-30 antibody, H-2K binding factor-2 antibody, immunoglobulin kappa J region recombination signal binding protein 1 antibody, recombining binding protein suppressor of hairless antibody, RBP-J kappa antibody, recombination signal binding protein for immunoglobulin kappa J region antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RBP-Jkappa. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (98%), Xenopus laevis (93%), Rhesus Monkey (99%), Bovine (99%)|