|Full Name||regulator of chromosome condensation 1|
|Product Description||Rabbit polyclonal antibody to RCC1 (regulator of chromosome condensation 1)|
|Background||Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.|
|Synonyms||CHC1 antibody, RCC1-I antibody, SNHG3-RCC1 antibody, RCC1 antibody, cell cycle regulatory protein antibody, guanine nucleotide-releasing protein antibody, SNHG3-RCC1 readthrough transcript antibody, regulator of chromosome condensation antibody, regulator of chromosome condensation 1 antibody|
|Cellular Localization||Nucleus , Cytoplasm |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RCC1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Dog, Rabbit, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (93%), Rat (93%), Xenopus laevis (81%), Dog (96%), Rabbit (96%), Chimpanzee (100%), Bovine (95%)|