|Full Name||UPF1 regulator of nonsense transcripts homolog (yeast)|
|Product Description||Rabbit polyclonal antibody to RENT1 (RENT1 regulator of nonsense transcripts homolog (yeast))|
|Background||This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq]|
|Synonyms||FLJ43809 antibody, FLJ46894 antibody, HUPF1 antibody, KIAA0221 antibody, NORF1 antibody, RENT1 antibody, pNORF1 antibody, UPF1 antibody, delta helicase antibody, yeast Upf1p homolog antibody, up-frameshift mutation 1 homolog antibody, regulator of nonsense transcripts 1 antibody, nonsense mRNA reducing factor 1 antibody, ATP-dependent helicase RENT1 antibody, UP Frameshift 1 antibody, "smg-2 homolog, nonsense mediated mRNA decay factor antibody", up-frameshift suppressor 1 homolog antibody, UPF1 regulator of nonsense transcripts homolog (yeast) antibody|
|Cellular Localization||Cytoplasm , P-body |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RENT1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Zebrafish, Drosophila|
|Predict Reactivity Note||Mouse (100%), Zebrafish (98%), Drosophila (83%)|