|Full Name||replication factor C (activator 1) 1, 145kDa|
|Product Description||Rabbit Polyclonal antibody to RFC1 (replication factor C (activator 1) 1, 145kDa)|
|Background||The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability. [provided by RefSeq]|
|Synonyms||RECC1 Antibody, replication factor C (activator 1) 1, 145kDa Antibody, RFC140 Antibody, MHCBFB Antibody, PO-GA Antibody, A1 Antibody, RFC Antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human RFC1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (84%), Rat (80%)|