|Full Name||regulator of G-protein signaling 1|
|Product Description||Rabbit Polyclonal antibody to RGS1 (regulator of G-protein signaling 1)|
|Background||This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq]|
|Synonyms||1R20 antibody, BL34 antibody, IER1 antibody, IR20 antibody, RGS1 antibody, B-cell activation protein BL34 antibody, regulator of G-protein signaling 1 antibody, "immediate-early response 1, B-cell specific antibody", regulator of G-protein signalling 1 antibody, early response protein 1R20 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RGS1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (86%), Rhesus Monkey (97%), Bovine (90%)|