|Full Name||regulator of G-protein signaling 14|
|Product Description||Rabbit Polyclonal antibody to RGS14 (regulator of G-protein signaling 14)|
|Background||This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]|
|Synonyms||regulator of G-protein signaling 14 Antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human RGS14. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Rat, Bovine|
|Predict Reactivity Note||Human (100%), Rat (90%), Bovine (100%)|