|Full Name||regulator of G-protein signaling 4|
|Product Description||Rabbit Polyclonal antibody to RGS4 (regulator of G-protein signaling 4)|
|Background||Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]|
|Synonyms||DKFZp761F1924 antibody, MGC2124 antibody, MGC60244 antibody, RGP4 antibody, SCZD9 antibody, RGS4 antibody, regulator of G-protein signaling 4 antibody, schizophrenia disorder 9 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RGS4. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Rabbit, Sheep, Bovine|
|Predict Reactivity Note||Pig (94%), Rabbit (95%), Sheep (96%), Bovine (96%)|