|Full Name||ring finger protein 14|
|Product Description||Rabbit Polyclonal antibody to RNF14 (ring finger protein 14)|
|Background||The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq]|
|Synonyms||ARA54 antibody, FLJ26004 antibody, HFB30 antibody, TRIAD2 antibody, RNF14 antibody, androgen receptor-associated protein 54 antibody, androgen receptor associated protein 54 antibody, E3 ubiquitin-protein ligase RNF14 antibody, ring finger protein 14 antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human RNF14. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Mouse (92%), Rat (92%), Rhesus Monkey (99%), Bovine (95%)|