| Full Name | ring finger protein 170 |
| Background | This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] |
| Synonyms | RNF170 Antibody , SNAX1 Antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | A synthetic peptide corresponding to an Internal region of Human RNF170 |
| Antigen Species | Human |
| Species Reactivity | Human |
| Predict Reactivity Note | Cow: 91%; Dog: 81%; Horse: 75%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93% |
| Conjugation | Unconjugated |