Full Name | ring finger protein 40 |
Background | The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. [provided by RefSeq] |
Synonyms | BRE1B antibody, DKFZp686K191 antibody, KIAA0661 antibody, MGC13051 antibody, RBP95 antibody, STARING antibody, RNF40 antibody, E3 ubiquitin-protein ligase BRE1B antibody, Rb-associated protein antibody, 95 kDa retinoblastoma-associated protein antibody, BRE1-B antibody, BRE1 E3 ubiquitin ligase homolog B antibody, 95 kDa retinoblastoma protein binding protein antibody, ring finger protein 40 antibody |
Cellular Localization | Nucleus |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein encompassing a sequence within the center region of human RNF40. The exact sequence is proprietary. |
Antigen Species | Human |
Species Reactivity | Human |
Predicted Cross Reactivity species Predicted cross-reactivity: Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive. Please note that we are only able to guarantee products to work in applications and species in which they have been tested. | Mouse, Rat, Rhesus Monkey, Bovine |
Predict Reactivity Note | Mouse (84%), Rat (84%), Rhesus Monkey (97%), Bovine (87%) |
Conjugation | Unconjugated |